Séminaire thématique bis2 - atlas single-cell et méthodes de déconvolution : leçons apprises et défis

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### PROGRAM 9:00 - 9:10 | Introduction **IGDR** 9:10 - 9:40 Lucie Lamothe (Invited speaker, UGA UMR 5217, LIG, Grenoble) * “A consensus-driven framework for building and sharing single-cell atlases applied to pancreatic ductal adenocarcinoma” 9:40 - 9:55 Luna Devemy (IGDR / Institut du Thorax, Nantes) * “Understanding the protective effects of oleic acid in obese mice through single-nucleus reference-based deconvolution” **Institut Agro - PEGASE, INRAE** 9:55 - 10:10 Fabien Degalez * “Generation of a single-nucleus atlas of the adult chicken liver: impact of genome annotations and resolution approaches” 10:10 - 10:25 Guillaume Cossard * “Single-cell guided deconvolution of RNAseq data from liver tissue of egg-laying hens: optimisation with benchmark data” 10:30 - 11:00 Coffee break **Oncogenesis, Stress & Signaling (OSS)** 11:00 - 11:20 Flavie Benard (OMICs team, Inserm U1242, Université de Rennes) * “Defining malignant cell states in glioblastoma by comparing gene signatures and scoring tools in published transcriptomics (single-cell and spatial) datasets” **MOBIDIC** 11:20 - 11:50 Charles Brottier & Judikael Saout (Laboratoire SITI / Inserm U1236) * “Deconvolution in Follicular Lymphoma : The Interplay Between Single-Cell References and Deconvolution Approaches” 11:50 - 12:10 Valentin Isen & Valeria Chahwan (Inserm U1236) * “Integrating without erasing biological variations: how to build and transfer an atlas with strong batch effects” 12:10 - 12:15 Concluding remarks Contact: [**Yuna Blum**](https://igdr.univ-rennes.fr/yuna-blum-0) [**Télécharger l'affiche**](https://igd